The present investigation intends to verify the effects of affective / cognitive aspects of well-being, here considered respectively as subjective happiness (Lyubormirsky & Lepper, 1999) and satisfaction with life (Diener, Emmons, Larsen, & Griffin, 1985), on felt / perceived disability from low back pain (Roland & Morris, 1983) in university students and Portuguese workers. Considered as a serious health problem for those who experience it and for the community where they operate, it is also a dysfunction responsible for high annual expenses in its treatment and in work licenses (Monteiro, 2012). In this initial stage, we intend to evaluate the role of happiness orientation (Peterson, Park, & Seligman, 2005) in the relationship between well-being (affective / cognitive) and the perception of disability due to low back pain. An empirical study of a quantitative nature will be carried out and with the application of the research protocol in two moments, whose data collection will be structured and operationalized through the survey method, using the technique of the self-administered questionnaire (Moreira, 2004). A structural model of relationships between the studied variables will be proposed. It is intended to expand knowledge about antecedents that can contribute to the prevention of disability created from low back pain, expanding the nomological network of the concept (Cronbach & Meehl, 1955).